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Masako Fujioka-Kobayashi


Visiting Research Fellow
Nationality: Japanese

Dr. Masako Fujioka-Kobayashi is a maxillofacial surgeon and assistant professor at Tokushima University, Japan. She was awarded a 2-year fellowship from Japan to study at the University of Bern where her primary focus is directed to her research activities. Since April 1st, 2016, she traveled to Fort Lauderdale, Florida to continue to work in the Miron Lab where she currently investigates a wide range of growth factors capable of bone or periodontal regeneration in combination with either bone grafting materials or collagen membranes. Given that her most recent discoveries led to excellent publications on recombinant human bone morphogenetic protein-9 (rhBMP9), she travelled to Southern Florida to continue her investigation on the bone-inducing properties of BMP9 for future clinical applications. Masako has authored or co-authored over 10 peer-reviewed articles since joining the Miron Lab less than 1 year ago.



2009-2013                   PhD, Department of Oral Surgery, Tokushima University Japan

2010-2012                   Special Research Student, Section of Molecular Craniofacial Embryology,                                                 Tokyo Medical and Dental University, Tokyo, Japan

2002-2008                   Doctor of Dental Surgery (DDS), Tokushima University, Japan


Academic Appointments

2016-Present              Visiting Research Scholar, Department of Periodontology, Nova                                                                 Southeastern University, Fort Lauderdale, Florida

2015-Present              Visiting Research Scholar, Department of Cranio Maxillofacial Surgery,                                                     University of Bern, Switzerland

2013-Present              Assistant Professor, Department Oral Surgery, Institute of Biomedical                                                       Sciences, Tokushima University Graduate School, Tokushima, Japan

2011-2013                   Research Fellow (DC2) Japan Society for the Promotion of Sciences

2009-2010                  Clinical Fellow, Department of Oral surgery, Tokushima University Hospital,                                             Tokushima, Japan

2008-2009                  Resident, Division of Oral and Maxillofacial Surgery, Kagawa Prefectural                                                   Central Hospital, Kagawa, Japan

Publications with the Miron Lab


  1. Fujioka-Kobayashi M, Sawada K, Kobayashi E, Schaller B, Zhang Y, Miron RJ. Osteogenic potential of rhBMP9 combined with a bovine derived natural bone mineral scaffold compared to rhBMP2. Clinical Oral Implants Research. 2016 Mar 14. doi: 10.1111/clr.12804.

  2. Miron RJ, Fujioka-Kobayashi M, Zhang, Y, Caballe-Serrano J, Shirakata Y, Bosshardt DD, Buser D, Sculean A. Osteogain improves osteoblast adhesion, proliferation and differentiation on a bovine-derived natural bone mineral. Clinical Oral Implants Research. 2016 Feb 26. doi: 10.1111/clr.12802.

  3. Caballé-Serrano J, Fujioka-Kobayashi M, Bosshardt DD, Gruber R, Buser D, Miron RJ. Pre-coating deproteinized bovine bone mineral (DBBM) with bone-conditioned medium (BCM) improves osteoblast migration, adhesion and differentiation in vitro. Clinical Oral Investigations. 2016 Feb 15.

  4. Kobayashi E, Flückiger L, Fujioka-Kobayashi M, Sawada K, Sculean A, Schaller B, Miron RJ. Comparative release of growth factors from PRP, PRF, and advanced-PRF. Clinical Oral Investigations. 2016 Jan 25. [Epub ahead of print].

  5. Fujioka-Kobayashi M, Sawada K, Kobayashi E, Schaller B, Zhang Y, Miron RJ. Recombinant Human Bone Morphogenetic Protein 9 (rhBMP9) Induced Osteoblastic Behaviour on a Collagen Membrane Compared With rhBMP2. Journal of Periodontology. 2016 Jan 11:1-14. [Epub ahead of print]

  6. Miron RJ, Fujioka-Kobayashi M, Zhang Y, Buser D, Bosshardt DD, Sculean A Combination of a collagen barrier membrane with Osteogain improves osteoblast adhesion and differentiation. Accepted in Journal of Oral Maxillofacial Implants (accepted but not yet online).

  7. Sawada K, Fujioka-Kobayashi M, Kobayashi E, Schaller B, Miron RJ. Effects of antiseptic solutions commonly used in dentistry on bone viability, bone morphology and release of growth factors. Journal of Oral Maxillofacial Surgery. 2016 Feb;74(2):247-54.

  8. Fujioka-Kobayashi M, Caballe-Serrano J, Bosshardt DD, Gruber R, Buser D, Miron RJ. Bone conditioned media (BCM) improves cell adhesion and osteoblast differentiation on collagen barrier membranes. (BMC Oral Health, not yet online)

  9. Sawada K, Fujioka-Kobayashi M, Kobayashi E, Bromme JO, Schaller B, Miron RJ. In vitro effects of 0 to 120 Grays of irradiation on bone viability and release of growth factors. (BMC Oral Health, not yet online)

  10. Mueller A, Fujioka-Kobayashi M, Mueller HD, Lussi A, Sculean A, Schmidlin P, Miron RJ. Effect of Hyaluronic Acid on Morphological Changes to Dentin Surfaces and Subsequent Effect on Periodontal Ligament Cell Survival, Attachment and Spreading. Under review in Clinical Oral Investigations.

  11. Shuang Y, Yizhen L, Zhang Y, Fujioka-Kobayashi M, Sculean A, Miron RJ. In vitro characterization of an osteoinductive biphasic calcium phosphate in combination with recombinant BMP2. Under review, BMC Oral Health.

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